TTC5 is required to prevent apoptosis of acute myeloid leukemia stem cells

Using a screening strategy, we identified the tetratricopeptide repeat (TPR) motif protein, Tetratricopeptide repeat domain 5 (TTC5, also known as stress responsive activator of p300 or Strap) as required for the survival of human acute myeloid leukemia (AML) cells. TTC5 is a stress-inducible transc...

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Detalles Bibliográficos
Autores principales: Lynch, J T, Somerville, T D D, Spencer, G J, Huang, X, Somervaille, T C P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641330/
https://www.ncbi.nlm.nih.gov/pubmed/23559008
http://dx.doi.org/10.1038/cddis.2013.107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641330/
https://www.ncbi.nlm.nih.gov/pubmed/23559008
http://dx.doi.org/10.1038/cddis.2013.107

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