A DR6/p75(NTR) complex is responsible for β-amyloid-induced cortical neuron death

The p75 neurotrophin receptor (p75(NTR)) is a known mediator of β-amyloid (Aβ)-induced neurotoxicity implicated in Alzheimer's disease (AD). Here, we demonstrate that death receptor 6 (DR6) binds to p75(NTR) and is a component of the p75(NTR) signaling complex responsible for Aβ-induced cortica...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Y, Lee, X, Shao, Z, Apicco, D, Huang, G, Gong, B J, Pepinsky, R B, Mi, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641333/
https://www.ncbi.nlm.nih.gov/pubmed/23559013
http://dx.doi.org/10.1038/cddis.2013.110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641333/
https://www.ncbi.nlm.nih.gov/pubmed/23559013
http://dx.doi.org/10.1038/cddis.2013.110

Ejemplares similares