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Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies

Neuroprotective therapies based on brain-derived neurotrophic factor (BDNF) administration have been proposed for Huntington's disease (HD) treatment. However, our group has recently reported reduced levels of TrkB in HD mouse models and HD human brain suggesting that besides a decrease on BDNF...

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Detalles Bibliográficos
Autores principales: Brito, V, Puigdellívol, M, Giralt, A, del Toro, D, Alberch, J, Ginés, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641339/
https://www.ncbi.nlm.nih.gov/pubmed/23598407
http://dx.doi.org/10.1038/cddis.2013.116