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ADAR1 is essential for intestinal homeostasis and stem cell maintenance

Adenosine deaminase acting on RNA 1 (ADAR1) is a double-stranded RNA-editing enzyme that converts adenosine (A) to inosine (I), and essential for normal development. In this study, we reported an essential role of ADAR1 in the survival and maintenance of intestinal stem cells and intestinal homoeost...

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Detalles Bibliográficos
Autores principales: Qiu, W, Wang, X, Buchanan, M, He, K, Sharma, R, Zhang, L, Wang, Q, Yu, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641348/
https://www.ncbi.nlm.nih.gov/pubmed/23598411
http://dx.doi.org/10.1038/cddis.2013.125