A non-catalytic role of choline kinase alpha is important in promoting cancer cell survival

Choline kinase alpha (ChoKα) is regarded as an attractive cancer target. The enzyme catalyses the formation of phosphocholine (PCho), an important precursor in the generation of phospholipids essential for cell growth. ChoKα has oncogenic properties and is critical for the survival of cancer cells....

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Detalles Bibliográficos
Autores principales: Falcon, S C, Hudson, C S, Huang, Y, Mortimore, M, Golec, J M, Charlton, P A, Weber, P, Sundaram, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641355/
https://www.ncbi.nlm.nih.gov/pubmed/25522435
http://dx.doi.org/10.1038/oncsis.2013.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641355/
https://www.ncbi.nlm.nih.gov/pubmed/25522435
http://dx.doi.org/10.1038/oncsis.2013.2

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