Cargando…

Downregulation of miRNA-31 induces taxane resistance in ovarian cancer cells through increase of receptor tyrosine kinase MET

Ovarian cancer is one of the most aggressive female reproductive tract tumors. Paclitaxel (PTX) is widely used for the treatment of ovarian cancer. However, ovarian cancers often acquire chemotherapeutic resistance to this agent. We investigated the mechanism of chemoresistance by analysis of microR...

Descripción completa

Detalles Bibliográficos
Autores principales: Mitamura, T, Watari, H, Wang, L, Kanno, H, Hassan, M K, Miyazaki, M, Katoh, Y, Kimura, T, Tanino, M, Nishihara, H, Tanaka, S, Sakuragi, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641356/
https://www.ncbi.nlm.nih.gov/pubmed/23552883
http://dx.doi.org/10.1038/oncsis.2013.3