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Retinoic acid represses invasion and stem cell phenotype by induction of the metastasis suppressors RARRES1 and LXN

The mouse haematopoietic stem cell (SC) regulator Latexin (LXN) is the only known homologue of the retinoic acid receptor responder 1 (RARRES1) gene. Both genes lie adjacent on chromosome 3 and differ mostly by the presence of a transmembrane domain in RARRES1. Despite their homology, it is not know...

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Detalles Bibliográficos
Autores principales: Oldridge, E E, Walker, H F, Stower, M J, Simms, M S, Mann, V M, Collins, A T, Pellacani, D, Maitland, N J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641360/
https://www.ncbi.nlm.nih.gov/pubmed/23588494
http://dx.doi.org/10.1038/oncsis.2013.6