Identification of tumorigenic and therapeutically actionable mutations in transplantable mouse tumor cells by exome sequencing

Cancer development occurs in response to the successive accumulation of mutations that eventually targets key regulators of cell proliferation. As most mutations likely occur randomly, cancer driver mutations can only be found if they are recurrent. Here we use exome sequencing of the mouse cell lin...

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Detalles Bibliográficos
Autores principales: Bhadury, J, López, M D, Muralidharan, S V, Nilsson, L M, Nilsson, J A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641362/
https://www.ncbi.nlm.nih.gov/pubmed/23588493
http://dx.doi.org/10.1038/oncsis.2013.8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641362/
https://www.ncbi.nlm.nih.gov/pubmed/23588493
http://dx.doi.org/10.1038/oncsis.2013.8

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