PKCα and PKCβ cooperate functionally in CD3-induced de novo IL-2 mRNA transcription

The physiological functions of PKCα and PKCθ isotypes downstream of the antigen receptor have been defined in CD3(+) T cells. In contrast, no function of the second conventional PKC member, PKCβ, has been described yet in T cell antigen receptor signalling. To investigate the hypothesis that both co...

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Detalles Bibliográficos
Autores principales: Christina, Lutz-Nicoladoni, Nikolaus, Thuille, Katarzyna, Wachowicz, Thomas, Gruber, Michael, Leitges, Gottfried, Baier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641392/
https://www.ncbi.nlm.nih.gov/pubmed/23439007
http://dx.doi.org/10.1016/j.imlet.2013.02.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641392/
https://www.ncbi.nlm.nih.gov/pubmed/23439007
http://dx.doi.org/10.1016/j.imlet.2013.02.002

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