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The colchicine derivative CT20126 shows a novel microtubule-modulating activity with apoptosis

New colchicine analogs have been synthesized with the aim of developing stronger potential anticancer activities. Among the analogs, CT20126 has been previously reported to show immunosuppressive activities. Here, we report that CT20126 also shows potential anticancer effects via an unusual mechanis...

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Detalles Bibliográficos
Autores principales: Kim, Sung-Kuk, Cho, Sang-Min, Kim, Ho, Seok, Heon, Kim, Soon-Ok, Kyu Kwon, Taeg, Chang, Jong-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641401/
https://www.ncbi.nlm.nih.gov/pubmed/23598593
http://dx.doi.org/10.1038/emm.2013.38