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The colchicine derivative CT20126 shows a novel microtubule-modulating activity with apoptosis
New colchicine analogs have been synthesized with the aim of developing stronger potential anticancer activities. Among the analogs, CT20126 has been previously reported to show immunosuppressive activities. Here, we report that CT20126 also shows potential anticancer effects via an unusual mechanis...
Autores principales: | Kim, Sung-Kuk, Cho, Sang-Min, Kim, Ho, Seok, Heon, Kim, Soon-Ok, Kyu Kwon, Taeg, Chang, Jong-Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641401/ https://www.ncbi.nlm.nih.gov/pubmed/23598593 http://dx.doi.org/10.1038/emm.2013.38 |
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