Association of dopamine-related genetic loci to dopamine D3 receptor antagonist ABT-925 clinical response

ABT-925, a selective dopamine D(3) receptor (DRD3) antagonist, was tested in schizophrenia. A DRD3 gene polymorphism results in an S9G amino-acid change that has been associated with lower risk of schizophrenia, higher affinity for dopamine and some antipsychotics, and differential response to some...

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Detalles Bibliográficos
Autores principales: Bhathena, A, Wang, Y, Kraft, J B, Idler, K B, Abel, S J, Holley-Shanks, R R, Robieson, W Z, Spear, B, Redden, L, Katz, D A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641409/
https://www.ncbi.nlm.nih.gov/pubmed/23571810
http://dx.doi.org/10.1038/tp.2013.22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641409/
https://www.ncbi.nlm.nih.gov/pubmed/23571810
http://dx.doi.org/10.1038/tp.2013.22

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