ErbB inhibitors ameliorate behavioral impairments of an animal model for schizophrenia: implication of their dopamine-modulatory actions

Ligands for ErbB receptors, including epidermal growth factor (EGF) and neuregulin-1, have a neurotrophic activity on midbrain dopaminergic neurons and are implicated in the pathophysiology of schizophrenia. Although ErbB kinase inhibitors ameliorate behavioral deficits of the schizophrenia model th...

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Detalles Bibliográficos
Autores principales: Mizuno, M, Sotoyama, H, Namba, H, Shibuya, M, Eda, T, Wang, R, Okubo, T, Nagata, K, Iwakura, Y, Nawa, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641415/
https://www.ncbi.nlm.nih.gov/pubmed/23632456
http://dx.doi.org/10.1038/tp.2013.29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641415/
https://www.ncbi.nlm.nih.gov/pubmed/23632456
http://dx.doi.org/10.1038/tp.2013.29

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