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BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities

The therapeutic activity of selective serotonin (5-HT) reuptake inhibitors (SSRIs) relies on long-term adaptation at pre- and post-synaptic levels. The sustained administration of SSRIs increases the serotonergic neurotransmission in response to a functional desensitization of the inhibitory 5-HT(1A...

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Detalles Bibliográficos
Autores principales: Quesseveur, G, David, D J, Gaillard, M C, Pla, P, Wu, M V, Nguyen, H T, Nicolas, V, Auregan, G, David, I, Dranovsky, A, Hantraye, P, Hen, R, Gardier, A M, Déglon, N, Guiard, B P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641417/
https://www.ncbi.nlm.nih.gov/pubmed/23632457
http://dx.doi.org/10.1038/tp.2013.30