Renal function estimations and dose recommendations for dabigatran, gabapentin and valaciclovir: a data simulation study focused on the elderly

OBJECTIVES: The thrombin inhibitor dabigatran is mainly excreted by the kidneys. We investigated whether the recommended method for estimation of renal function used in the clinical trials, the Cockcroft-Gault (CG(old)) equation and the estimated glomerular filtration rate (eGFR) modification of die...

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Detalles Bibliográficos
Autores principales: Helldén, Anders, Odar-Cederlöf, Ingegerd, Nilsson, Göran, Sjöviker, Susanne, Söderström, Anders, von Euler, Mia, Öhlén, Gunnar, Bergman, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2013
Materias:
Geriatric Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641460/
https://www.ncbi.nlm.nih.gov/pubmed/23585393
http://dx.doi.org/10.1136/bmjopen-2013-002686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641460/
https://www.ncbi.nlm.nih.gov/pubmed/23585393
http://dx.doi.org/10.1136/bmjopen-2013-002686

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