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Phospholipase D signaling mediates reactive oxygen species-induced lung endothelial barrier dysfunction

Reactive oxygen species (ROS) have emerged as critical players in the pathophysiology of pulmonary disorders and diseases. Earlier, we have demonstrated that ROS stimulate lung endothelial cell (EC) phospholipase D (PLD) that generates phosphatidic acid (PA), a second messenger involved in signal tr...

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Detalles Bibliográficos
Autores principales: Usatyuk, Peter V., Kotha, Sainath R., Parinandi, Narasimham L., Natarajan, Viswanathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641713/
https://www.ncbi.nlm.nih.gov/pubmed/23662182
http://dx.doi.org/10.4103/2045-8932.109925