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Predicting substrates of the human breast cancer resistance protein using a support vector machine method

BACKGROUND: Human breast cancer resistance protein (BCRP) is an ATP-binding cassette (ABC) efflux transporter that confers multidrug resistance in cancers and also plays an important role in the absorption, distribution and elimination of drugs. Prediction as to if drugs or new molecular entities ar...

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Detalles Bibliográficos
Autores principales: Hazai, Eszter, Hazai, Istvan, Ragueneau-Majlessi, Isabelle, Chung, Sophie P, Bikadi, Zsolt, Mao, Qingcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641962/
https://www.ncbi.nlm.nih.gov/pubmed/23586520
http://dx.doi.org/10.1186/1471-2105-14-130