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Predicting substrates of the human breast cancer resistance protein using a support vector machine method
BACKGROUND: Human breast cancer resistance protein (BCRP) is an ATP-binding cassette (ABC) efflux transporter that confers multidrug resistance in cancers and also plays an important role in the absorption, distribution and elimination of drugs. Prediction as to if drugs or new molecular entities ar...
Autores principales: | Hazai, Eszter, Hazai, Istvan, Ragueneau-Majlessi, Isabelle, Chung, Sophie P, Bikadi, Zsolt, Mao, Qingcheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641962/ https://www.ncbi.nlm.nih.gov/pubmed/23586520 http://dx.doi.org/10.1186/1471-2105-14-130 |
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