Whole-genome sequencing in an autism multiplex family

BACKGROUND: Autism spectrum disorders (ASDs) represent a group of childhood neurodevelopmental disorders that affect 1 in 88 children in the US. Previous exome sequencing studies on family trios have implicated a role for rare, de-novo mutations in the pathogenesis of autism. METHODS: To examine the...

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Detalles Bibliográficos
Autores principales: Shi, Lingling, Zhang, Xu, Golhar, Ryan, Otieno, Frederick G, He, Mingze, Hou, Cuiping, Kim, Cecilia, Keating, Brendan, Lyon, Gholson J, Wang, Kai, Hakonarson, Hakon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642023/
https://www.ncbi.nlm.nih.gov/pubmed/23597238
http://dx.doi.org/10.1186/2040-2392-4-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642023/
https://www.ncbi.nlm.nih.gov/pubmed/23597238
http://dx.doi.org/10.1186/2040-2392-4-8

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