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Whole-genome sequencing in an autism multiplex family

BACKGROUND: Autism spectrum disorders (ASDs) represent a group of childhood neurodevelopmental disorders that affect 1 in 88 children in the US. Previous exome sequencing studies on family trios have implicated a role for rare, de-novo mutations in the pathogenesis of autism. METHODS: To examine the...

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Detalles Bibliográficos
Autores principales:	Shi, Lingling, Zhang, Xu, Golhar, Ryan, Otieno, Frederick G, He, Mingze, Hou, Cuiping, Kim, Cecilia, Keating, Brendan, Lyon, Gholson J, Wang, Kai, Hakonarson, Hakon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642023/ https://www.ncbi.nlm.nih.gov/pubmed/23597238 http://dx.doi.org/10.1186/2040-2392-4-8

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