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The protective effect and underlying mechanism of metformin on neointima formation in fructose-induced insulin resistant rats

BACKGROUND: Insulin resistance is strongly associated with the development of type 2 diabetes and cardiovascular disease. However, the underlying mechanisms linking insulin resistance and the development of atherosclerosis have not been fully elucidated. Moreover, the protective effect of antihyperg...

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Detalles Bibliográficos
Autores principales: Lu, Jianxin, Ji, Jingzhang, Meng, Howard, Wang, David, Jiang, Bo, Liu, Lixin, Randell, Edward, Adeli, Khosrow, Meng, Qing H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642024/
https://www.ncbi.nlm.nih.gov/pubmed/23561047
http://dx.doi.org/10.1186/1475-2840-12-58