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Probing the Energy Landscape of Activation Gating of the Bacterial Potassium Channel KcsA

The bacterial potassium channel KcsA, which has been crystallized in several conformations, offers an ideal model to investigate activation gating of ion channels. In this study, essential dynamics simulations are applied to obtain insights into the transition pathways and the energy profile of KcsA...

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Detalles Bibliográficos
Autores principales: Linder, Tobias, de Groot, Bert L., Stary-Weinzinger, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642040/
https://www.ncbi.nlm.nih.gov/pubmed/23658510
http://dx.doi.org/10.1371/journal.pcbi.1003058