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Probing the Energy Landscape of Activation Gating of the Bacterial Potassium Channel KcsA
The bacterial potassium channel KcsA, which has been crystallized in several conformations, offers an ideal model to investigate activation gating of ion channels. In this study, essential dynamics simulations are applied to obtain insights into the transition pathways and the energy profile of KcsA...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642040/ https://www.ncbi.nlm.nih.gov/pubmed/23658510 http://dx.doi.org/10.1371/journal.pcbi.1003058 |