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Attachment Site Selection and Identity in Bxb1 Serine Integrase-Mediated Site-Specific Recombination

Phage-encoded serine integrases mediate directionally regulated site-specific recombination between short attP and attB DNA sites without host factor requirements. These features make them attractive for genome engineering and synthetic genetics, although the basis for DNA site selection is poorly u...

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Detalles Bibliográficos
Autores principales: Singh, Shweta, Ghosh, Pallavi, Hatfull, Graham F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642061/
https://www.ncbi.nlm.nih.gov/pubmed/23658531
http://dx.doi.org/10.1371/journal.pgen.1003490