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Inhibitory effects of choline-O-sulfate on amyloid formation of human islet amyloid polypeptide

Choline-O-sulfate (2-(trimethylammonio)ethyl sulfate, COS) is a naturally occurring osmolyte that is synthesized by plants, lichens, algae, fungi, and several bacterial species. We examined the inhibitory effects of COS on amyloid formation of the human islet amyloid polypeptide (hIAPP or amylin) us...

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Detalles Bibliográficos
Autores principales: Hagihara, Mamoru, Takei, Ayaka, Ishii, Takeshi, Hayashi, Fumio, Kubota, Kenji, Wakamatsu, Kaori, Nameki, Nobukazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642097/
https://www.ncbi.nlm.nih.gov/pubmed/23650576
http://dx.doi.org/10.1016/j.fob.2012.02.001