The Wnt pathway destabilizes adherens junctions and promotes cell migration via β-catenin and its target gene cyclin D1

The Wnt pathway regulates cell proliferation, mobility and differentiation. Among the many Wnt target genes is CCND1 which codes for cyclin D1. Cyclin D1, in complex with cdk4 and cdk6, regulates G1/S phase transition during cell cycle. Independently of CDK, cyclin D1 also regulates the migration of...

Descripción completa

Detalles Bibliográficos
Autores principales: Vlad-Fiegen, Annica, Langerak, Anette, Eberth, Sonja, Müller, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642111/
https://www.ncbi.nlm.nih.gov/pubmed/23650577
http://dx.doi.org/10.1016/j.fob.2012.02.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642111/
https://www.ncbi.nlm.nih.gov/pubmed/23650577
http://dx.doi.org/10.1016/j.fob.2012.02.004

Ejemplares similares