The anti-atherosclerotic di-peptide, Trp-His, inhibits the phosphorylation of voltage-dependent L-type Ca(2+) channels in rat vascular smooth muscle cells

Trp-His is the only vasoactive di-peptide known to regulate intracellular Ca(2+) ([Ca(2+)](i)) and prevent the onset of atherosclerosis in mice. In this study, we showed that Trp-His reduced the [Ca(2+)](i) elevation in phospholipase C-activated vascular smooth muscle cells (VSMCs), while a mixture...

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Detalles Bibliográficos
Autores principales: Kobayashi, Yutaro, Fukuda, Toshihiko, Tanaka, Mitsuru, Matsui, Toshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642122/
https://www.ncbi.nlm.nih.gov/pubmed/23650584
http://dx.doi.org/10.1016/j.fob.2012.04.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642122/
https://www.ncbi.nlm.nih.gov/pubmed/23650584
http://dx.doi.org/10.1016/j.fob.2012.04.005

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