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The anti-atherosclerotic di-peptide, Trp-His, inhibits the phosphorylation of voltage-dependent L-type Ca(2+) channels in rat vascular smooth muscle cells
Trp-His is the only vasoactive di-peptide known to regulate intracellular Ca(2+) ([Ca(2+)](i)) and prevent the onset of atherosclerosis in mice. In this study, we showed that Trp-His reduced the [Ca(2+)](i) elevation in phospholipase C-activated vascular smooth muscle cells (VSMCs), while a mixture...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642122/ https://www.ncbi.nlm.nih.gov/pubmed/23650584 http://dx.doi.org/10.1016/j.fob.2012.04.005 |