Distinguishable In Vitro Binding Mode of Monomeric TRBP and Dimeric PACT with siRNA

RNA interference (RNAi) is an evolutionally conserved posttranscriptional gene-silencing mechanism whereby small interfering RNA (siRNA) triggers sequence-specific cleavage of its cognate mRNA. Dicer, Argonaute (Ago), and either TAR-RNA binding protein (TRBP) or a protein activator of PKR (PACT) are...

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Detalles Bibliográficos
Autores principales: Takahashi, Tomoko, Miyakawa, Takuya, Zenno, Shuhei, Nishi, Kenji, Tanokura, Masaru, Ui-Tei, Kumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642127/
https://www.ncbi.nlm.nih.gov/pubmed/23658827
http://dx.doi.org/10.1371/journal.pone.0063434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642127/
https://www.ncbi.nlm.nih.gov/pubmed/23658827
http://dx.doi.org/10.1371/journal.pone.0063434

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