Cargando…
Distinguishable In Vitro Binding Mode of Monomeric TRBP and Dimeric PACT with siRNA
RNA interference (RNAi) is an evolutionally conserved posttranscriptional gene-silencing mechanism whereby small interfering RNA (siRNA) triggers sequence-specific cleavage of its cognate mRNA. Dicer, Argonaute (Ago), and either TAR-RNA binding protein (TRBP) or a protein activator of PKR (PACT) are...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642127/ https://www.ncbi.nlm.nih.gov/pubmed/23658827 http://dx.doi.org/10.1371/journal.pone.0063434 |