Mithramycin Targets Sp1 and The Androgen Receptor Transcription Level—Potential Therapeutic Role in Advanced Prostate Cancer

Multiple lines of evidence implicate over-expression and activation of the androgen receptor (AR) in the progression of prostate cancer (PC) to androgen-independence (AI) and resistance to therapy. The mechanisms leading to AR over-expression are not fully understood but binding of Sp1 to specific S...

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Detalles Bibliográficos
Autores principales: Wang, Long G., Ferrari, Anna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2006
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642134/
https://www.ncbi.nlm.nih.gov/pubmed/23662037

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