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The manner in which DNA is packaged with TFAM has an impact on transcription activation and inhibition

For successful mitochondrial transgene expression, an optimal packaging exogenous DNA is an important issue. We report herein on the effects of DNA packaged with mitochondrial transcription factor A (TFAM), which packages mitochondrial DNA (mtDNA), on the transcription process. Our initial findings...

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Detalles Bibliográficos
Autores principales: Furukawa, Ryo, Yamada, Yuma, Matsushima, Yuichi, Goto, Yu-ichi, Harashima, Hideyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642137/
https://www.ncbi.nlm.nih.gov/pubmed/23650593
http://dx.doi.org/10.1016/j.fob.2012.06.001