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Insulin-Mediated Activation of the L-Arginine Nitric Oxide Pathway in Man, and Its Impairment in Diabetes

AIMS/HYPOTHESIS: Impaired L-arginine transport has been reported in cardiovascular diseases, providing a possible mechanism for reduced nitric oxide (NO) production. Given that cardiovascular diseases are also associated with insulin resistance, and insulin is known to induce vasodilation via a NO-d...

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Detalles Bibliográficos
Autores principales: Rajapakse, Niwanthi W., Chong, Abigail L., Zhang, Wei-Zheng, Kaye, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642141/
https://www.ncbi.nlm.nih.gov/pubmed/23658699
http://dx.doi.org/10.1371/journal.pone.0061840