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Metabolic Turnover of Synaptic Proteins: Kinetics, Interdependencies and Implications for Synaptic Maintenance

Chemical synapses contain multitudes of proteins, which in common with all proteins, have finite lifetimes and therefore need to be continuously replaced. Given the huge numbers of synaptic connections typical neurons form, the demand to maintain the protein contents of these connections might be ex...

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Detalles Bibliográficos
Autores principales: Cohen, Laurie D., Zuchman, Rina, Sorokina, Oksana, Müller, Anke, Dieterich, Daniela C., Armstrong, J. Douglas, Ziv, Tamar, Ziv, Noam E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642143/
https://www.ncbi.nlm.nih.gov/pubmed/23658807
http://dx.doi.org/10.1371/journal.pone.0063191