Evolution of an inhibitory RNA aptamer against T7 RNA polymerase

Aptamers are promising gene components that can be used for the construction of synthetic gene circuits. In this study, we isolated an RNA aptamer that specifically inhibits transcription of T7 RNA polymerase (RNAP). The 38-nucleotide aptamer, which was a shortened variant of an initial SELEX isolat...

Descripción completa

Detalles Bibliográficos
Autores principales: Ohuchi, Shoji, Mori, Yusuke, Nakamura, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642155/
https://www.ncbi.nlm.nih.gov/pubmed/23650601
http://dx.doi.org/10.1016/j.fob.2012.07.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642155/
https://www.ncbi.nlm.nih.gov/pubmed/23650601
http://dx.doi.org/10.1016/j.fob.2012.07.004

Ejemplares similares