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c-Met Mutational Analysis in the Sema and Juxtamembrane Domains in Small-Cell-Lung-Cancer

BACKGROUND: c-Met mutations play a critical role in the development and progression of primary tumors and metastases. Activation of the HGF/SF-c-Met pathway determines a poor prognosis in non-small-cell and small-cell lung cancer (SCLC) patients. Missense mutations of c-Met have been identified in S...

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Detalles Bibliográficos
Autores principales: de Aguirre, Itziar, Salvatierra, Alejandro, Font, Albert, Mate, Jose Luis, Perez, Maria, Botia, Monica, Taron, Miquel, Rosell, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642244/
https://www.ncbi.nlm.nih.gov/pubmed/23662036