Mutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing miR-27a expression

p53 is a major tumor suppressor whose function is pivotal for protection against cancer. In over half of human cancers, p53 is inactivated due to either point mutation or loss of p53 gene. It has been well established that in addition to abrogating the tumor-suppressive function of wild-type p53, mu...

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Detalles Bibliográficos
Autores principales: Wang, W, Cheng, B, Miao, L, Mei, Y, Wu, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642368/
https://www.ncbi.nlm.nih.gov/pubmed/23559009
http://dx.doi.org/10.1038/cddis.2013.97

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642368/
https://www.ncbi.nlm.nih.gov/pubmed/23559009
http://dx.doi.org/10.1038/cddis.2013.97

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