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From essential to persistent genes: a functional approach to constructing synthetic life

A central undertaking in synthetic biology (SB) is the quest for the ‘minimal genome’. However, ‘minimal sets’ of essential genes are strongly context-dependent and, in all prokaryotic genomes sequenced to date, not a single protein-coding gene is entirely conserved. Furthermore, a lack of consensus...

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Detalles Bibliográficos
Autores principales: Acevedo-Rocha, Carlos G., Fang, Gang, Schmidt, Markus, Ussery, David W., Danchin, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Trends Journals 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642372/
https://www.ncbi.nlm.nih.gov/pubmed/23219343
http://dx.doi.org/10.1016/j.tig.2012.11.001