Distinct roles for Sir2 and RNAi in centromeric heterochromatin nucleation, spreading and maintenance

Epigenetically regulated heterochromatin domains govern essential cellular activities. A key feature of heterochromatin domains is the presence of hypoacetylated nucleosomes, which are methylated on lysine 9 of histone H3 (H3K9me). Here, we investigate the requirements for establishment, spreading a...

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Detalles Bibliográficos
Autores principales: Buscaino, Alessia, Lejeune, Erwan, Audergon, Pauline, Hamilton, Georgina, Pidoux, Alison, Allshire, Robin C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642681/
https://www.ncbi.nlm.nih.gov/pubmed/23572080
http://dx.doi.org/10.1038/emboj.2013.72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642681/
https://www.ncbi.nlm.nih.gov/pubmed/23572080
http://dx.doi.org/10.1038/emboj.2013.72

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