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The integration of HR-HPV increases the expression of cyclins A and E in cytologies with and without low-grade lesions
BACKGROUND: Cyclin-A and cyclin-E are regulators of G1–S phase of normal cell cycle. Integration of human papilloma virus high-risk (HR-HPV) could alter this mechanism, and its overexpression has been associated with poor prognosis in cervical cancer. AIM: To determine the expression of cyclin-A and...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643354/ https://www.ncbi.nlm.nih.gov/pubmed/23661932 http://dx.doi.org/10.4103/0970-9371.107504 |