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The integration of HR-HPV increases the expression of cyclins A and E in cytologies with and without low-grade lesions

BACKGROUND: Cyclin-A and cyclin-E are regulators of G1–S phase of normal cell cycle. Integration of human papilloma virus high-risk (HR-HPV) could alter this mechanism, and its overexpression has been associated with poor prognosis in cervical cancer. AIM: To determine the expression of cyclin-A and...

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Detalles Bibliográficos
Autores principales: Zubillaga-Guerrero, MI, Illades-Aguiar, B, Leyva-Vazquez, MA, Flores-Alfaro, E, Castañeda-Saucedo, E, Muñoz-Valle, JF, Alarcón-Romero, LC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643354/
https://www.ncbi.nlm.nih.gov/pubmed/23661932
http://dx.doi.org/10.4103/0970-9371.107504