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A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli
The Y-family DNA polymerase IV or PolIV (Escherichia coli) is the founding member of the DinB family and is known to play an important role in stress-induced mutagenesis. We have determined four crystal structures of this enzyme in its pre-catalytic state in complex with substrate DNA presenting the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643571/ https://www.ncbi.nlm.nih.gov/pubmed/23525461 http://dx.doi.org/10.1093/nar/gkt146 |