A rapid and sensitive assay for DNA–protein covalent complexes in living cells

A number of proteins form covalent bonds with DNA as obligatory transient intermediates in normal nuclear transactions. Drugs that trap these complexes have proven to be potent therapeutics in both cancer and infectious disease. Nonetheless, current assays for DNA–protein adducts are cumbersome, lim...

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Detalles Bibliográficos
Autores principales: Kiianitsa, Kostantin, Maizels, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643584/
https://www.ncbi.nlm.nih.gov/pubmed/23519618
http://dx.doi.org/10.1093/nar/gkt171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643584/
https://www.ncbi.nlm.nih.gov/pubmed/23519618
http://dx.doi.org/10.1093/nar/gkt171

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