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A rapid and sensitive assay for DNA–protein covalent complexes in living cells
A number of proteins form covalent bonds with DNA as obligatory transient intermediates in normal nuclear transactions. Drugs that trap these complexes have proven to be potent therapeutics in both cancer and infectious disease. Nonetheless, current assays for DNA–protein adducts are cumbersome, lim...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643584/ https://www.ncbi.nlm.nih.gov/pubmed/23519618 http://dx.doi.org/10.1093/nar/gkt171 |