Leucine-specific domain modulates the aminoacylation and proofreading functional cycle of bacterial leucyl-tRNA synthetase

The leucine-specific domain (LSD) is a compact well-ordered module that participates in positioning of the conserved KMSKS catalytic loop in most leucyl-tRNA synthetases (LeuRSs). However, the LeuRS from Mycoplasma mobile (MmLeuRS) has a tetrapeptide GKDG instead of the LSD. Here, we show that the t...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Wei, Tan, Min, Eriani, Gilbert, Wang, En-Duo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643597/
https://www.ncbi.nlm.nih.gov/pubmed/23525458
http://dx.doi.org/10.1093/nar/gkt185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643597/
https://www.ncbi.nlm.nih.gov/pubmed/23525458
http://dx.doi.org/10.1093/nar/gkt185

Ejemplares similares