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Kinesin KIFC1 actively transports bare double-stranded DNA

During the past years, exogenous DNA molecules have been used in gene and molecular therapy. At present, it is not known how these DNA molecules reach the cell nucleus. We used an in cell single-molecule approach to observe the motion of exogenous short DNA molecules in the cytoplasm of eukaryotic c...

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Detalles Bibliográficos
Autores principales: Farina, Francesca, Pierobon, Paolo, Delevoye, Cédric, Monnet, Jordan, Dingli, Florent, Loew, Damarys, Quanz, Maria, Dutreix, Marie, Cappello, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643607/
https://www.ncbi.nlm.nih.gov/pubmed/23543461
http://dx.doi.org/10.1093/nar/gkt204