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Tyrosine 23 Phosphorylation of Annexin A2 Promotes Proliferation, Invasion, and Stat3 Phosphorylation in the Nucleus of Human Breast Cancer SK-BR-3 Cells

OBJECTIVE: To investigate the role of tyrosine 23 (Tyr23) phosphorylation of Annexin A2 (Anxa2) in regulating the proliferation and invasion of human breast cancer SK-BR-3 cells. METHODS: A panel of lentivirus plasmids expressing Anxa2-wide type (Ana2-WT), Anxa2-Y23A, and Anxa2-Y23D was generated an...

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Detalles Bibliográficos
Autores principales: Wang, Yu-qing, Zhang, Fei, Tian, Ran, Ji, Wei, Zhou, Yan, Sun, Xiu-mei, Liu, Yuan, Wang, Zhi-yong, Niu, Rui-fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643677/
https://www.ncbi.nlm.nih.gov/pubmed/23691485
http://dx.doi.org/10.7497/j.issn.2095-3941.2012.04.005