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A novel t(3;12)(q21;p13) translocation in a patient with accelerated chronic myeloid leukemia after imatinib and nilotinib therapy

The acquisition of secondary chromosomal aberrations in chronic myeloid leukemia (CML) patients with Philadelphia chromosome-positive (Ph+) karyotype signifies clonal evolution associated with the progression of the disease to its accelerated or blastic phase. Therefore, these aberrations have clini...

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Detalles Bibliográficos
Autores principales: Bennour, Ayda, Tabka, Ikram, Ben Youssef, Yosra, Kmeira, Zahra, Khelif, Abderrahim, Saad, Ali, Sennana, Halima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643689/
https://www.ncbi.nlm.nih.gov/pubmed/23691445
http://dx.doi.org/10.7497/j.issn.2095-3941.2013.01.008