Activation of conventional protein kinase C (PKC) is critical in the generation of human neutrophil extracellular traps

BACKGROUND: Activation of NADPH oxidase is required for neutrophil extracellular trap (NET) formation. Protein kinase C (PKC) is an upstream mediator of NADPH oxidase activation and thus likely to have a role in NET formation. METHODS: Pharmacological inhibitors were used to block PKC activity in ne...

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Detalles Bibliográficos
Autores principales: Gray, Robert D, Lucas, Christopher D, MacKellar, Annie, Li, Feng, Hiersemenzel, Katia, Haslett, Chris, Davidson, Donald J, Rossi, Adriano G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643828/
https://www.ncbi.nlm.nih.gov/pubmed/23514610
http://dx.doi.org/10.1186/1476-9255-10-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643828/
https://www.ncbi.nlm.nih.gov/pubmed/23514610
http://dx.doi.org/10.1186/1476-9255-10-12

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