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Activation of conventional protein kinase C (PKC) is critical in the generation of human neutrophil extracellular traps
BACKGROUND: Activation of NADPH oxidase is required for neutrophil extracellular trap (NET) formation. Protein kinase C (PKC) is an upstream mediator of NADPH oxidase activation and thus likely to have a role in NET formation. METHODS: Pharmacological inhibitors were used to block PKC activity in ne...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643828/ https://www.ncbi.nlm.nih.gov/pubmed/23514610 http://dx.doi.org/10.1186/1476-9255-10-12 |