Histone deacetylase inhibitors up-regulate LL-37 expression independent of toll-like receptor mediated signalling in airway epithelial cells

HDAC inhibitors have been proposed as anticancer agents. However, their roles in innate genes expression remain not well known. Cathelicidin LL-37 is one of the few human bactericidal peptides, but the regulation of histone acetylation on LL-37 expression in airway epithelium remains largely unknown...

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Detalles Bibliográficos
Autores principales: Liu, Quan, Liu, Juan, Roschmann, Kristina Irene Lisolette, van Egmond, Danielle, Golebski, Korneliusz, Fokkens, Wytske Johanna, Wang, Dehui, van Drunen, Cornelis Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643837/
https://www.ncbi.nlm.nih.gov/pubmed/23577829
http://dx.doi.org/10.1186/1476-9255-10-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643837/
https://www.ncbi.nlm.nih.gov/pubmed/23577829
http://dx.doi.org/10.1186/1476-9255-10-15

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